Dr. Urquidi's research involves the study of molecular liquids (e.g. water, HF, acetic acid) and amorphous materials (e.g. high & low density amorphous ice and optically relevant glasses) through the use of neutron and high energy X-ray diffraction techniques combined with molecular dynamic and reverse Monte Carlo simulations as aids in data interpretation. The benefits of using neutron scattering in conjunction with high energy X-rays for condensed matter research are considerable. They both serve as bulk probes due to their high penetrating power and yield complimentary structural information.

Urquidi's other research interests include the behaviour of liquid water at interfaces, with particular interest in biologically relevant surfaces and interactions. Also of interest to him is the relationship between supercooled water and the purported high to low density transition which may have implications to the existence of a second critical point for the liquid.